The identification of human-virus protein-protein interactions (PPIs) is an essential and challenging research topic, potentially providing a mechanistic understanding of viral infection.Given that the experimental determination of human-virus PPIs is time-consuming and labor-intensive, computational methods are playing an important role in providi
Abstract Background Tick-borne encephalitis (TBE) is the most common viral CNS infection with incidences much higher than all other virus infections together in many risk areas of central and eastern Europe.The Odenwald Hill region (OWH) in southwestern Germany is classified as a TBE risk region and frequent case numbers but also more severe infect
Rectal prolapse is defined as prolapse of all layers of rectal wallout of the anal sphincter.The aim was to (i) describe the IEC Connectors extremely rare combination of a rectal prolapse with colon cancer in an older female patient, (ii) comment on management-specific aspects and Ear Muff (iii) derive some generalizing recommendations by means of
ABSTRACT Cyclic GMP-AMP synthase (cGAS) is an important DNA pattern recognition receptor that senses double-stranded DNA derived from invading pathogens or self DNA in cytoplasm, leading to an antiviral interferon response.A tick-borne Bunyavirus, severe fever with thrombocytopenia syndrome virus (SFTSV), is an RNA virus that causes a severe emergi